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Fig. 1 | Cancer & Metabolism

Fig. 1

From: Isoform-specific deletion of PKM2 constrains tumor initiation in a mouse model of soft tissue sarcoma

Fig. 1

Human and mouse soft tissue sarcomas express PKM2. Representative images of IHC for PKM1 and PKM2 in human (a) and mouse (b) skeletal muscle and human rhabdomyosarcoma (c). Corresponding H&E images are shown. Scale bars, 20 μm. d Quantification of PKM1 and PKM2 staining intensities in human rhabdomyosarcoma tumors relative to rhabdomyosarcoma subtype (embryonal, spindle cells, alveolus, pleomorphic). Score 0 = no staining, score 1 = weak, score 2 = positive, or score 3 = strong

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Cancer & Metabolism

ISSN: 2049-3002