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Table 1 Patient and tumor characteristics

From: The effect of statin treatment on intratumoral cholesterol levels and LDL receptor expression: a window-of-opportunity breast cancer trial

  Completed all study parts Complete cholesterol pairs
  n = 42 n = 14
Age years (mean, range) 63 (35-89) 68 (50-83)
Tumor size mm (mean, range) 21 (6-33) 23 (13-32)
Tumor grade (NHG)   
 I 9 (21%) 4 (29%)
 II 17 (41%) 3 (21%)
 III 16 (38%) 7 (50%)
Mitotic index   
 1 23 (55%) 6 (43%)
 2 5 (12%) 1 (7%)
 3 14 (33%) 7 (50%)
ER (n = 30), baseline   
 Positive 27 (90%) 14 (100%)
 Negative 3 (10%) 0 (0%)
PR (n = 30), baseline   
 Positive 24(80%) 11 (79%)
 Negative 6 (20%) 3 (21%)
HER2 (n = 29), baseline   
 0 7 (24%) 4 (32%)
 1+ 10 (34%) 5 (38%)
 2+ 7 (24%) 2 (15%)
 3+ 5 (17%) 2 (15%)
Ki67 index (n = 26), baseline   
 Low 15 (58%) 7 (54%)
 High 11 (42%) 6 (46%)
HMGCR (n = 38)   
 Negative 14 (37%) 5 (38%)
 Positive 24 (63%) 8 (62%)
  1. NHG Nottingham histologic grade I-III (post-treatment pathological report), mitotic index according to Nottingham criteria (post-treatment pathological report), baseline tumor data (pretreatment): Ki67 high if >20%, HMGCR positive if any cytoplasmic staining, ER (estrogen receptor), PR (progesterone receptor), HER2 (human epidermal growth factor receptor 2)